Despite going on three death-defying adventures with gamers, not much is known about Nathan Drake in his past before he teamed up with Sully in Cartagena, Colombia back when he was just a teenage boy.
What gamers know about Drake was mostly derived from his conversation with Katherine Marlowe after he was drugged and taken to her in Yemen during the events of “Uncharted 3.”
Based on Marlowe’s file, when Drake turned five years old, his mother committed suicide and his father had relinquished custody of him to the state, leading to Nathan ending up in Saint Francis Boy’s Home.
The trailer of “Uncharted 4: A Thief’s End” during the PSX event also showed Nathan believing his brother to be dead after he saw him get shot. But the hole in the story is that even if Sam was presumed dead, critics are wondering why Marlowe did not bring up the fact to Drake.
She has mentioned to him his dead mother, so it is ironic why she did not twist the knife further and trudge up the past about his dead brother and how Drake abandoned him after Sam was shot. Nathan also did not bother to check if his own brother is still breathing or not before leaving him to bleed out.